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A causal role for uric acid in fructose-induced metabolic syndrome.

Am. J. Physiol. Renal Physiol. 2006 Mar;290(3):F625-31.
PubMed Citation Journal Link

The worldwide epidemic of metabolic syndrome correlates with an elevation in serum uric acid as well as a marked increase in total fructose intake (in the form of table sugar and high-fructo...syndrome, possibly due to its ability to inhibit endothelial function. Fructose may have a major role in the epidemic of metabolic syndrome and obesity due to its ability to raise uric acid.

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