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A controlled trial of reduced meal frequency without caloric restriction in healthy, normal-weight, middle-aged adults.

Am. J. Clin. Nutr. 2007 Apr;85(4):981-8.
PubMed Citation Journal Link

Although consumption of 3 meals/d is the most common pattern of eating in industrialized countries, a scientific rationale for this meal frequency with respect to optimal health is lacking. A diet with less meal frequency can improve the health and extend the lifespan of laboratory animals, but its effect on humans has never been tested.

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