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Acute effects of interferon-alpha administration on thyroid hormone metabolism in healthy men.

J. Clin. Endocrinol. Metab. 1995 Nov;80(11):3140-4.
PubMed Citation Journal Link

Both hyper- and hypothyroidism have been reported during prolonged recombinant human interferon-alpha (rhIFN alpha) therapy. To assess the short term effects of IFN alpha therapy on thyroid ...n part by IL-6. The acute effects of rhIFN alpha mimic the euthyroid sick syndrome and appear to be different from the effects of chronic rhIFN alpha treatment on thyroid hormone metabolism.

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