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Connecting the dots: molecular and epigenetic mechanisms in type 2 diabetes.

Curr Diabetes Rev 2010 Jul;6(4):255-65.
PubMed Citation Journal Link

It is likely that the heritability of T2DM goes beyond simple genetic markers and involves epigenetic mechanisms. Neel's Thrifty Gene Hypothesis was expanded by Chakravarthy to include metab... an opportune time to start connecting the dots to provide the much needed basis for a better understanding of T2DM and a more targeted approach to drug development and treatment strategies.

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