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D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease.

J. Clin. Invest. 2003 Sep;112(6):892-901.
PubMed Citation Journal Link

Parkinson disease (PD) is a neurodegenerative disorder characterized by a loss of the nigrostriatal dopaminergic neurons accompanied by a deficit in mitochondrial respiration. 1-Methyl-4-phe...ion. Because of the safety record of ketone bodies in the treatment of epilepsy and their ability to penetrate the blood-brain barrier, DbetaHB may be a novel neuroprotective therapy for PD.

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