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Defense of body weight depends on dietary composition and palatability in rats with diet-induced obesity.
Am. J. Physiol. Regul. Integr. Comp. Phy 2002 Jan;282(1):R46-54.
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Sprague-Dawley rats selectively bred for diet-induced obesity (DIO) or diet resistance (DR) were characterized on diets of differing energy content and palatability. Over 10 wk, DR rats on a...ntromedial hypothalamic nucleus. Thus genetic background, diet composition, and palatability interact to produce disparate levels of defended body weight and central neuropeptide expression.
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