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Fructose-induced leptin resistance exacerbates weight gain in response to subsequent high-fat feeding.

Am. J. Physiol. Regul. Integr. Comp. Phy 2008 Nov;295(5):R1370-5.
PubMed Citation Journal Link

It has been suggested that increased fructose intake is associated with obesity. We hypothesized that chronic fructose consumption causes leptin resistance, which subsequently may promote th...tion induces leptin resistance prior to body weight, adiposity, serum leptin, insulin, or glucose increases, and this fructose-induced leptin resistance accelerates high-fat induced obesity.

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