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Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention.

J. Clin. Endocrinol. Metab. 2007 May;92(5):1827-33.
PubMed Citation Journal Link

... CONCLUSIONS: These data provide evidence that the rs2267668 A/G SNP in PPARD and the Gly482Ser SNP in PPARGC1A have both independent and additive effects on the effectiveness of aerobic exercise training to increase aerobic physical fitness and insulin sensitivity.

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That's the Issue...G-Flux: E ? MC2

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