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Iron dysregulation in Alzheimer's disease: multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents.

Prog. Neurobiol. 2007 Aug;82(6):348-60.
PubMed Citation Journal Link

Considering the multi-etiological character of Alzheimer's disease (AD), the current pharmacological approaches using drugs oriented towards a single molecular target possess limited ability...allate (EGCG) and curcumin, reported to have access to the brain and to possess multifunctional activities, such as metal chelation-radical scavenging, anti-inflammation and neuroprotection.

1 Analysis


Iron, Oxidation, Inflammation, and Aging

Primal Wisdom
September 30, 2011
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