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Metabolic slowing with massive weight loss despite preservation of fat-free mass.

J. Clin. Endocrinol. Metab. 2012 Jul;97(7):2489-96.
PubMed Citation Journal Link

An important goal during weight loss is to maximize fat loss while preserving metabolically active fat-free mass (FFM). Massive weight loss typically results in substantial loss of FFM potentially slowing metabolic rate.

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