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Mortality over two centuries in large pedigree with familial hypercholesterolaemia: family tree mortality study.

BMJ 2001 Apr 28;322(7293):1019-23.
PubMed Citation Journal Link

... CONCLUSIONS: Risk of death varies significantly among patients with familial hypercholesterolaemia. This large variability over time and between branches of the pedigree points to a strong interaction with environmental factors. Future research is required to identify patients with familial hypercholesterolaemia who are at extreme risk and need early and vigorous preventive measures.

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