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Polycystic ovary syndrome and its developmental origins.

Rev Endocr Metab Disord 2007 Jun;8(2):127-41.
PubMed Citation Journal Link

The prenatal testosterone (T)-treated adult female rhesus monkey is one animal model of polycystic ovary syndrome (PCOS) in women, with early prenatal T excess programming a permanent of insulin action, including PCOS, obesity and diabetes mellitus as well as minimize transgenerational susceptibility to adult PCOS and its metabolic derangements in male close relatives.

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