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Potential link between interleukin-6 and arachidonic acid metabolism in Alzheimer's disease.

J. Neural Transm. Suppl. 1998;54:268-78.
PubMed Citation Journal Link

Prostaglandins (PGs) and cytokines, such as interleukin-1 (IL-1) and interleukin-6 (IL-6), have been implicated in the etiopathology of various inflammatory and degenerative disorders, inclu...hypothesized for Alzheimer's disease. Finally we demonstrate that microglia are a strong source of PGE2 synthesis indicating that these cells may act as the origin of the pathogenic cascade.

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