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The decline in plasma leptin in response to calorie restriction predicts the effects of adjunctive leptin treatment on body weight in humans.

Eur. J. Intern. Med. 2003 Nov;14(7):415-418.
PubMed Citation Journal Link

... CONCLUSION: Leptin administration counteracts the adaptations that are actuated by the drop in leptin concentrations and thereby disrupts energy balance to promote weight loss.

Community Experience

Paleo Diet for Weight Loss
12 reviews

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