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Vitamin D receptor gene polymorphism in rheumatoid arthritis and associated osteoporosis.

Rheumatol. Int. 2006 Sep;26(11):964-71.
PubMed Citation Journal Link

Rheumatoid arthritis (RA) is commonly associated with decreased bone mineral density (BMD) due to numerous factors. BsmI polymorphism of the vitamin D receptor (VDR) gene has been implicated...volved in the pathogenesis of RA-associated osteoporosis. The possible involvement of vitamin D and VDR gene polymorphisms in the development and progression of RA needs further elucidation.

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