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Paleo Diet for Acid Reflux / GERD

Paleo Diet for Acid Reflux / GERD

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Success stories and experiences on how the Paleo Diet has helped with Acid Reflux / GERD.

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From the Paleosphere

Athletic acid reflux. Hyperlipid (cites 2 articles) April 1, 2008
American Heart Association OKs Linoleic Acid and Arachidonic Acid. Cooling Inflammation February 4, 2009
RHR: Naturally Treating Heartburn, Infant Reflux, and Stroke Prevention. The Healthy Skeptic September 5, 2012
Is GERD an autoimmune disease?. The Healthy Skeptic (cites 2 articles) January 19, 2012
GERD: Symptoms, Causes and Remedies. Mark's Daily Apple (cites 1 article) September 7, 2011
Reader who cured GERD with low-carb diet interviewed on TV. The Healthy Skeptic May 9, 2010
Audio interview on how to cure heartburn and GERD without drugs. The Healthy Skeptic May 5, 2010
Getting off Proton Pump Inhibitor GERD Meds Cold Turkey. Free the Animal January 27, 2011
Folic Acid. Matt Metzgar (cites 4 articles) January 23, 2011
Battery acid and oatmeal. The Heart Scan Blog (cites 1 article) March 23, 2011
Battery acid and oatmeal. The Heart Scan Blog March 23, 2011
Want some acid? Bad trip on palmitic.... Hyperlipid (cites 1 article) September 17, 2009
Acid-Base Balance. Whole Health Source October 10, 2008
AGE RAGE and ALE: linoleic acid. Hyperlipid (cites 3 articles) September 2, 2008
Protons: TFAM and behenic acid. Hyperlipid (cites 2 articles) February 14, 2013
Protons: The linoleic acid fed mice. Hyperlipid (cites 1 article) January 19, 2013
Protons: Linoleic acid in the hypothalamus. Hyperlipid (cites 3 articles) September 17, 2012
Nuts and Phytic Acid: Should You Be Concerned?. Mark's Daily Apple (cites 9 articles) May 16, 2012
Palmitic acid: the horror never ends. Hyperlipid (cites 3 articles) April 13, 2011
Low Stomach Acid and Nutrient Absorption. Whole Health Source (cites 4 articles) February 13, 2009
The little known (but crucial) difference between folate and folic acid. The Healthy Skeptic (cites 8 articles) March 9, 2012
Palmitic acid: the horror never ends speculation. Hyperlipid (cites 1 article) April 17, 2011
Palmitic acid: the horror never ends addendum. Hyperlipid April 14, 2011
Omega 3 Fatty Acid and Adiponectin Levels. NephroPal December 19, 2009
Physiological insulin resistance and palmitic acid again. Hyperlipid (cites 1 article) September 19, 2009
Palmitic Acid and Insulin Resistance: a New Paradigm. Whole Health Source (cites 2 articles) September 19, 2009
Dr. Susie Rockway on conjugated linoleic acid (CLA). The Heart Scan Blog October 5, 2007
Arachidonic Acid and Breast, Prostate, and Colon Cancers. Primal Wisdom (cites 31 articles) March 1, 2012
Infant Milk Allergy, Colic and Sialic Acid. Cooling Inflammation June 17, 2010
Palmitic Acid+ CARBS = Mouse Skeletal Muscle IR. Animal Pharm (cites 12 articles) September 21, 2009
Omega-6 Linoleic Acid Suppresses Thyroid Signaling. Whole Health Source (cites 12 articles) December 20, 2008
Brain Arachidonic Acid: Alzheimer’s, Bipolar, Parkinson’s. Cooling Inflammation November 21, 2008
RHR: Overcoming Low Stomach Acid, Asthma, and Night Time Depression. The Healthy Skeptic (cites 1 article) January 30, 2013
Phytanic Acid (Red Meat, Dairy, Seafood): Binds PPAR-? and RXR. Animal Pharm (cites 21 articles) November 4, 2012
Phytanic Acid (Red Meat, Dairy, Seafood): Binds PPAR-? and RXR. NephroPal (cites 16 articles) June 12, 2010
Lack of association between fructose and high uric acid levels.. NephroPal (cites 1 article) May 29, 2010
Palmitic acid based food vs olive oil or corn oil supplements. Hyperlipid (cites 2 articles) September 18, 2009
Butyric Acid: an Ancient Controller of Metabolism, Inflammation and Stress Resistance. Whole Health Source (cites 14 articles) December 8, 2009
Estimated macronutrient and fatty acid intakes from an East African Paleolithic diet: Part 1. Primal Wisdom May 1, 2011

Research References

Estimated macronutrient and fatty acid intakes from an East African Paleolithic diet. Br. J. Nutr. 2010 Dec;104(11):1666-87. (cited by 6 analyses) April 2013
Conjugated linoleic acid in adipose tissue and risk of myocardial infarction. Am. J. Clin. Nutr. 2010 Jul;92(1):34-40. (cited by 4 analyses) January 2012
Effects of winter stocker growth rate and finishing system on: III. Tissue proximate, fatty acid, vitamin, and cholesterol content. J. Anim. Sci. 2009 Sep;87(9):2961-70. (cited by 4 analyses) April 2011
The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp. Biol. Med. (Maywood) 2008 Jun;233(6):674-88. (cited by 4 analyses) June 2010
Conjugated linoleic acid content of milk from cows fed different diets. J. Dairy Sci. 1999 Oct;82(10):2146-56. (cited by 4 analyses) November 2012
Conjugated linoleic acid reduces body fat mass in overweight and obese humans. J. Nutr. 2000 Dec;130(12):2943-8. (cited by 3 analyses) November 2012
Decreasing linoleic acid with constant alpha-linolenic acid in dietary fats increases (n-3) eicosapentaenoic acid in plasma phospholipids in healthy men. J. Nutr. 2007 Apr;137(4):945-52. (cited by 3 analyses) April 2011
A causal role for uric acid in fructose-induced metabolic syndrome. Am. J. Physiol. Renal Physiol. 2006 Mar;290(3):F625-31. (cited by 3 analyses) March 2013
Colon cancer in Chile before and after the start of the flour fortification program with folic acid. Eur J Gastroenterol Hepatol 2009 Apr;21(4):436-9. (cited by 3 analyses) March 2012
Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease. Lancet 1994 Jun 11;343(8911):1454-9. (cited by 3 analyses) June 2009
Phytic acid added to white-wheat bread inhibits fractional apparent magnesium absorption in humans. Am. J. Clin. Nutr. 2004 Mar;79(3):418-23. (cited by 3 analyses) April 2010
Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet 2007 Mar 31;369(9567):1090-8. (cited by 3 analyses) October 2008
A very low-carbohydrate diet improves gastroesophageal reflux and its symptoms. Dig. Dis. Sci. 2006 Aug;51(8):1307-12. (cited by 2 analyses) September 2011
Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts. J. Lipid Res. 1998 Jan;39(1):66-74. (cited by 2 analyses) November 2012
The metabolism of phytanic acid and pristanic acid in man: a review. J. Inherit. Metab. Dis. 1998 Oct;21(7):697-728. (cited by 2 analyses) November 2012
Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance. Circulation 2002 Oct 8;106(15):1925-9. (cited by 2 analyses) May 2011
Fatty acid composition of plasma phospholipids and risk of prostate cancer. Am. J. Clin. Nutr. 2009 Jun;89(6):1946; author reply 1. (cited by 2 analyses) April 2011
Total fat intake modifies plasma fatty acid composition in humans. J. Nutr. 2001 Feb;131(2):231-4. (cited by 2 analyses) April 2011
A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef. Nutr J 2010;9:10. (cited by 2 analyses) March 2013
Erythrocyte fatty acid profiles can predict acute non-fatal myocardial infarction. Br. J. Nutr. 2009 Nov;102(9):1355-61. (cited by 2 analyses) February 2010
Folic acid and risk of prostate cancer: results from a randomized clinical trial. J. Natl. Cancer Inst. 2009 Mar 18;101(6):432-5. (cited by 2 analyses) March 2012
Conjugated linoleic acid supplementation for 1 y reduces body fat mass in healthy overweight humans. Am. J. Clin. Nutr. 2004 Jun;79(6):1118-25. (cited by 2 analyses) November 2012
Relationship between n-3 and n-6 plasma fatty acid levels and insulin resistance in coronary patients with and without metabolic syndrome. Nutr Metab Cardiovasc Dis 2009 May;19(4):264-70. (cited by 2 analyses) September 2012
Comparison of muscle fatty acid profiles and cholesterol concentrations of bison, beef cattle, elk, and chicken. J. Anim. Sci. 2002 May;80(5):1202-11. (cited by 2 analyses) March 2013
Arachidonic acid supplementation enhances synthesis of eicosanoids without suppressing immune functions in young healthy men. Lipids 1998 Feb;33(2):125-30. (cited by 2 analyses) April 2013
Treatment with dietary trans10cis12 conjugated linoleic acid causes isomer-specific insulin resistance in obese men with the metabolic syndrome. Diabetes Care 2002 Sep;25(9):1516-21. (cited by 2 analyses) May 2011
Lipoprotein profiles and serum peroxide levels of aged women consuming palmolein or oleic acid-rich sunflower oil diets. Eur J Clin Nutr 1998 Sep;52(9):675-83. (cited by 2 analyses) January 2012
No evidence of differential effects of SFA, MUFA or PUFA on post-ingestive satiety and energy intake: a randomised trial of fatty acid saturation. Nutr J 2010;9:24. (cited by 2 analyses) November 2010
Diet and disease--the Israeli paradox: possible dangers of a high omega-6 polyunsaturated fatty acid diet. Isr. J. Med. Sci. 1996 Nov;32(11):1134-43. (cited by 2 analyses) February 2012
An omega-3 polyunsaturated fatty acid concentrate increases plasma high-density lipoprotein 2 cholesterol and paraoxonase levels in patients with familial combined hyperlipidemia. Metab. Clin. Exp. 2004 Feb;53(2):153-8. (cited by 2 analyses) July 2009
Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study. Aliment. Pharmacol. Ther. 2006 Apr 15;23(8):1143-51. (cited by 2 analyses) September 2008
Effect of feeding systems on omega-3 fatty acids, conjugated linoleic acid and trans fatty acids in Australian beef cuts: potential impact on human health. Asia Pac J Clin Nutr 2006;15(1):21-9. (cited by 2 analyses) November 2011
Effects of stearic acid on plasma lipid and lipoproteins in humans. Lipids 2005 Dec;40(12):1201-5. (cited by 2 analyses) May 2012
Oral sensitivity to oleic acid is associated with fat intake and body mass index. Clin Nutr 2011 Dec;30(6):838-44. (cited by 2 analyses) March 2012
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nature immunology 2011 Apr 10. (cited by 2 analyses) April 2011
(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G. J. Biol. Chem. 2005 Jul 22;280(29):26649-52. (cited by 2 analyses) October 2008
Feeding regimes affect fatty acid composition in Australian beef cattle. Asia Pac J Clin Nutr 2003;12:S38. (cited by 2 analyses) August 2008
Carcinogen-induced lesions in the rat pancreas: effects of varying levels of essential fatty acid. Cancer Res. 1985 Nov;45(11):5252-6. (cited by 2 analyses) January 2009
Inverse association between dietary and serum conjugated linoleic acid and risk of breast cancer in postmenopausal women. Nutr Cancer 2000;38(2):151-7. (cited by 2 analyses) November 2012
Dietary lipid profile is a determinant of tissue phospholipid fatty acid composition and rate of weight gain in rats. J. Nutr. 1993 Mar;123(3):512-9. (cited by 2 analyses) January 2010
Western diet, but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats. Biochem. J. 2007 Sep 15;406(3):457-67. (cited by 2 analyses) September 2009
Use of dietary linoleic acid for secondary prevention of coronary heart disease and death: evaluation of recovered data from the Sydney Diet Heart Study and updated meta-analysis. BMJ 2013;346:e8707. (cited by 2 analyses) February 2013
Long-term effect of varying the source or amount of dietary carbohydrate on postprandial plasma glucose, insulin, triacylglycerol, and free fatty acid concentrations in subjects with impaired glucose tolerance. Am. J. Clin. Nutr. 2003 Mar;77(3):612-21. (cited by 2 analyses) March 2009
Oxygen radicals shaping evolution: why fatty acid catabolism leads to peroxisomes while neurons do without it: FADH?/NADH flux ratios determining mitochondrial radical formation were crucial for the eukaryotic invention of peroxisomes and catabolic tissue differentiation. Bioessays 2011 Feb;33(2):88-94. (cited by 2 analyses) August 2012
Gastroesophageal reflux might cause esophagitis through a cytokine-mediated mechanism rather than caustic acid injury. Gastroenterology 2009 Nov;137(5):1776-84. (cited by 1 analysis) January 2012
Gastroesophageal reflux in athletes. Curr Sports Med Rep 2004 Apr;3(2):107-11. (cited by 1 analysis) April 2008
Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease. Gastroenterology 2003 Apr;124(4):894-902. (cited by 1 analysis) February 2010
Dietary linoleic acid has no effect on arachidonic acid, but increases n-6 eicosadienoic acid, and lowers dihomo-gamma-linolenic and eicosapentaenoic acid in plasma of adult men. Prostaglandins Leukot. Essent. Fatty Aci 2009 Apr;80(4):201-6. (cited by 1 analysis) April 2011
Anti-obesity effects of conjugated linoleic acid, docosahexaenoic acid, and eicosapentaenoic acid. Mol Nutr Food Res 2008 Jun;52(6):631-45. (cited by 1 analysis) May 2010
Manganese absorption in humans: the effect of phytic acid and ascorbic acid in soy formula. Am. J. Clin. Nutr. 1995 Nov;62(5):984-7. (cited by 1 analysis) May 2012
Uric acid production of men fed graded amounts of egg protein and yeast nucleic acid. Am. J. Clin. Nutr. 1968 Sep;21(9):892-7. (cited by 1 analysis) January 2013
Impact of linoleic acid intake on arachidonic acid formation and eicosanoid biosynthesis in humans. Prostaglandins Leukot. Essent. Fatty Aci 1998 Apr;79(3):177-81. (cited by 1 analysis) March 2012
Human essential fatty acid deficiency: treatment by topical application of linoleic acid. Arch Dermatol 1977 Jul;113(7):939-41. (cited by 1 analysis) August 2012
Cell proliferation inhibition and alterations in retinol esterification induced by phytanic acid and docosahexaenoic acid. J. Lipid Res. 2007 Jan;48(1):165-76. (cited by 1 analysis) November 2012
Phytanic acid--an overlooked bioactive fatty acid in dairy fat? Ann. N. Y. Acad. Sci. 2010 Mar;1190:42-9. (cited by 1 analysis) November 2012
Etheno-DNA adduct formation in rats gavaged with linoleic acid, oleic acid and coconut oil is organ- and gender specific. Mutat. Res. 2007 Nov 1;624(1):71-9. (cited by 1 analysis) October 2009
Dietary supplementation with gamma-linolenic acid alters fatty acid content and eicosanoid production in healthy humans. J. Nutr. 1997 Aug;127(8):1435-44. (cited by 1 analysis) October 2012
EFFECT OF LINOLEIC ACID UPON THE METABOLISM OF LINOLENIC ACID. J. Nutr. 1964 Sep;84:15-9. (cited by 1 analysis) September 2008
Effects of docosahexaenoic acid-rich n-3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study. Am. J. Clin. Nutr. 2008 Jun;87(6):1616-22. (cited by 1 analysis) April 2010
Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver. Br. J. Nutr. 2007 Jan;97(1):58-66. (cited by 1 analysis) May 2011
Increasing dietary linoleic acid does not increase tissue arachidonic acid content in adults consuming Western-type diets: a systematic review. Nutr Metab (Lond) 2011;8:36. (cited by 1 analysis) March 2012
Deficits in docosahexaenoic acid and associated elevations in the metabolism of arachidonic acid and saturated fatty acids in the postmortem orbitofrontal cortex of patients with bipolar disorder. Psychiatry Res 2008 Sep 30;160(3):285-99. (cited by 1 analysis) January 2009
Influence of dietary linoleic acid intake with different fat intakes on arachidonic acid concentrations in plasma and platelet lipids and eicosanoid biosynthesis in female volunteers. Ann. Nutr. Metab. 2003;47(1):31-6. (cited by 1 analysis) March 2012
Omega-3 fatty acid docosahexaenoic acid increases SorLA/LR11, a sorting protein with reduced expression in sporadic Alzheimer's disease (AD): relevance to AD prevention. J. Neurosci. 2007 Dec 26;27(52):14299-307. (cited by 1 analysis) June 2011
Absorption of eicosapentaenoic acid and docosahexaenoic acid from fish oil triacylglycerols or fish oil ethyl esters co-ingested with a high-fat meal. Biochem. Biophys. Res. Commun. 1988 Oct 31;156(2):960-3. (cited by 1 analysis) May 2010
Nutritional intervention to reduce the n-6/n-3 fatty acid ratio increases adiponectin concentration and fatty acid oxidation in healthy subjects. Eur J Clin Nutr 2008 Nov;62(11):1287-93. (cited by 1 analysis) December 2008
Effect of alpha-linolenic acid-rich Camelina sativa oil on serum fatty acid composition and serum lipids in hypercholesterolemic subjects. Metab. Clin. Exp. 2002 Oct;51(10):1253-60. (cited by 1 analysis) June 2011
Conjugated linolenic acid is slowly absorbed in rat intestine, but quickly converted to conjugated linoleic acid. J. Nutr. 2006 Aug;136(8):2153-9. (cited by 1 analysis) January 2012
Unmetabolized serum folic acid and its relation to folic acid intake from diet and supplements in a nationally representative sample of adults aged > or =60 y in the United States. Am. J. Clin. Nutr. 2010 Aug;92(2):383-9. (cited by 1 analysis) January 2011
Fatty acid composition, including conjugated linoleic acid, of intramuscular fat from steers offered grazed grass, grass silage, or concentrate-based diets. J. Anim. Sci. 2000 Nov;78(11):2849-55. (cited by 1 analysis) January 2008
n-3 and n-6 fatty acid intake and serum phospholipid fatty acid composition in middle-aged women living in rural and urban areas in Okayama Prefecture. J. Nutr. Sci. Vitaminol. 1995 Jun;41(3):313-23. (cited by 1 analysis) December 2010
Flaxseed oil and fish-oil capsule consumption alters human red blood cell n-3 fatty acid composition: a multiple-dosing trial comparing 2 sources of n-3 fatty acid. Am. J. Clin. Nutr. 2008 Sep;88(3):801-9. (cited by 1 analysis) December 2008
Relationship between fatty acid delivery and fatty acid oxidation during strenuous exercise. J. Appl. Physiol. 1995 Dec;79(6):1939-45. (cited by 1 analysis) May 2010
Folic acid, pyridoxine, and cyanocobalamin combination treatment and age-related macular degeneration in women: the Women's Antioxidant and Folic Acid Cardiovascular Study. Arch. Intern. Med. 2009 Feb 23;169(4):335-41. (cited by 1 analysis) August 2011
An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women. J. Nutr. 2008 Aug;138(8):1445-51. (cited by 1 analysis) May 2011
Folic acid under scrutiny. Br. J. Nutr. 2007 Oct;98(4):665-6. (cited by 1 analysis) March 2012
Nicotinic acid/niacinamide and the skin. J Cosmet Dermatol 2004 Apr;3(2):88-93. (cited by 1 analysis) June 2010
Psoriasis and the arachidonic acid cascade. J. Dermatol. Sci. 1999 Nov;21(3):135-46. (cited by 1 analysis) March 2012
Bioavailability of marine n-3 fatty acid formulations. Prostaglandins Leukot. Essent. Fatty Aci 2010 Sep;83(3):137-41. (cited by 1 analysis) February 2011
Nicotinic acid receptor subtypes and their ligands. Med Res Rev 2007 May;27(3):417-33. (cited by 1 analysis) October 2007
Arachidonic acid and ischemic heart disease. J. Nutr. 2005 Sep;135(9):2271-3. (cited by 1 analysis) March 2012
The tricarboxylic acid cycle of Helicobacter pylori. Eur. J. Biochem. 1999 Feb;260(1):258-67. (cited by 1 analysis) March 2008
Contribution of meat fat to dietary arachidonic acid. Lipids 1998 Apr;33(4):437-40. (cited by 1 analysis) March 2012
The proteolytic system of lactic acid bacteria. Microbiologia 1993 Dec;9(2):90-106. (cited by 1 analysis) March 2008
Lactic acid bacteria and human health. Ann. Med. 1990 Feb;22(1):37-41. (cited by 1 analysis) March 2008
Disorders related to the metabolism of phytanic acid. Scand. J. Clin. Lab. Invest. Suppl. 1986;184:3-10. (cited by 1 analysis) November 2012
Inability of bats to synthesise L-ascorbic acid 1976 Apr;260(5552):626. (cited by 1 analysis) February 2010
Phytic acid and nutritional rickets in immigrants. Lancet 1972 Apr 8;1(7754):771-3. (cited by 1 analysis) September 2011
Multiple changes in sialic acid biology during human evolution Glycoconjugate Journal null;26(3):231. (cited by 1 analysis) April 2013
Sex-specific differences in essential fatty acid metabolism. Am. J. Clin. Nutr. 2011 Dec;94(6):1914S-1919S. (cited by 1 analysis) August 2012
Harmful, harmless or helpful? The n-6 fatty acid debate goes on. Curr Opin Clin Nutr Metab Care 2011 Mar;14(2):113-4. (cited by 1 analysis) February 2013
Caught red-handed: uric acid is an agent of inflammation. J. Clin. Invest. 2010 Jun 1;120(6):1809-11. (cited by 1 analysis) August 2011
Vitamin C intake and serum uric acid concentration in men. J. Rheumatol. 2008 Sep;35(9):1853-8. (cited by 1 analysis) April 2012
Food fortification with folic acid: has the other shoe dropped? Nutr. Rev. 2007 Nov;65(11):512-5. (cited by 1 analysis) March 2012
Adipose tissue biomarkers of fatty acid intake. Am. J. Clin. Nutr. 2002 Oct;76(4):750-7. (cited by 1 analysis) April 2010
Effect of insulin on uric acid excretion in humans. Am. J. Physiol. 1995 Jan;268(1):E1-5. (cited by 1 analysis) April 2012
Omeprazole: blocks gastric acid secretion completely. Drug Ther Bull 1990 Jun 25;28(13):49-52. (cited by 1 analysis) January 2013
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