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Paleo Diet for Drug Toxicity

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Success stories and experiences on how the Paleo Diet has helped with Drug Toxicity.

From the Paleosphere

• Court Case: How One Drug Company "Buried" Evidence Showing Its Drug Caused Diabetes. Diabetes Update February 27, 2009
• Januvia 3rd Most Heavily Marketed Drug - VT Drug Disclosure Document. Diabetes Update July 14, 2008
• What Does That Pharmaceutical Drug Actually Do? This Question Never Answered Before Drug Approval!. Diabetes Update (cites 1 article) February 13, 2008
• Vitamin D toxicity. The Heart Scan Blog (cites 1 article) February 6, 2008
• Vitamin D toxicity?. The Heart Scan Blog May 30, 2007
• Is Vitamin A Toxicity a Concern?. Whole Health Source November 18, 2008
• Links & Commentary: Cavemen in the News; Vitamin A Toxicity; and Saturated Fat Will Kill You. Free the Animal (cites 1 article) March 23, 2010
• Drug Use today. Conditioning Research November 8, 2011
• Which statin drug is best?. The Heart Scan Blog (cites 1 article) February 8, 2009
• Welfare Drug Testing. Matt Metzgar March 7, 2012
• The costs of doing drug business?. The Heart Scan Blog January 5, 2011
• Statin drug revolt. The Heart Scan Blog December 16, 2008
• Taking a Drug Holiday. Diabetes Update July 12, 2007
• "Drug no cure for gluttony". The Heart Scan Blog May 24, 2007
• Are we a front for drug companies?. The Heart Scan Blog May 1, 2007
• Vitamin D: New Miracle Drug. The Heart Scan Blog December 6, 2006
• Drug Cessation and Weight Gain. Whole Health Source (cites 4 articles) June 24, 2011
• I Warned Them This Drug Might Kill People.... The Daily Lipid (cites 4 articles) November 30, 2010
• Drug Free for the First Time in Five Years. Mark's Daily Apple November 5, 2010
• Diabetes Drug Interactions Can Harm You. Diabetes Update September 13, 2010
• No. I Am NOT Paranoid about Drug Company Evildoing. Diabetes Update July 13, 2010
• FDA approves drug for the annoyingly cheerful. The Healthy Skeptic May 3, 2010
• Drug industry "Deep Throat". The Heart Scan Blog June 18, 2009
• How Much Did Drug Companies Pay Your Doctor Last Year?. Diabetes Update July 10, 2008
• Qnexa, the Latest FDA Approved Obesity Drug. Whole Health Source (cites 1 article) March 17, 2012
• Is direct-to-consumer drug marketing a failure?. The Heart Scan Blog (cites 1 article) April 23, 2008
• More Spinning Statistics to Promote Statins by Drug Cos?. Diabetes Update October 11, 2007
• Drug Approval: Diabetes is NOT Advanced Cancer. Diabetes Update June 11, 2007
• Corrupt Drug Regulator Sentenced to Death. Diabetes Update May 29, 2007
• Januvia Revisited - Results of my Own Trial of This New Drug. Diabetes Update January 15, 2007
• Is Your Doctor Getting Cash Payouts from Big Pharma? (plus More Findings from the Drug Biz). Mark's Daily Apple October 20, 2010
• Database Reveals Drug Company Payments to Doctors. Diabetes Update October 19, 2010
• Familial Hypercholesterolemia: Is Taking A Statin Drug The Only Solution?. Jimmy Moore's Livin' La Vida Low Carb Blog July 21, 2010
• Santa Claus is alive . . . and works for the drug industry. The Heart Scan Blog December 12, 2008
• Statin Drug Manufacturers Deluge Media with Spin. Diabetes Update January 30, 2008
• Yet Another Drug Study Shows Lowering LDL Does Not Affect Clogging of Arteries. Diabetes Update May 7, 2008
• Study: Studies funded by Drug Makers Underestimate Problems. Diabetes Update (cites 1 article) November 13, 2007
• Chronicles of Evil: Documented Drug Company Malfeasance Puts You At Risk. Diabetes Update November 21, 2008
• Diabetes Does Not Create Risk Just like Having Had a Heart Attack: Another Drug Company Myth Debunked. Diabetes Update (cites 1 article) September 2, 2010
• Fun-Filled Friday: Health Care, March Madness, Drug Ads, Tom Naughton, Scale, Internet, Ice Skating, Parental Pressure. Jimmy Moore's Livin' La Vida Low Carb Blog March 27, 2010

Research References

• Experimental acute toxicity of xylitol in dogs. J. Vet. Pharmacol. Ther. 2009 Oct;32(5):465-9. (cited by 2 analyses) February 2011
• Drug-induced hypochlorhydria causes high duodenal bacterial counts in the elderly. Aliment. Pharmacol. Ther. 1998 Jan;12(1):99-104. (cited by 2 analyses) February 2009
• Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity. Toxicol. Appl. Pharmacol. 2009 Jul 15;238(2):150-9. (cited by 1 analysis) December 2010
• Anti-mycobacterial activity of garlic (Allium sativum) against multi-drug resistant and non-multi-drug resistant mycobacterium tuberculosis. Pak J Pharm Sci 2011 Jan;24(1):81-5. (cited by 1 analysis) November 2011
• Pharmacokinetics of vitamin D toxicity. Am. J. Clin. Nutr. 2008 Aug;88(2):582S-586S. (cited by 1 analysis) October 2009
• Drug-induced autoimmunity. Curr Opin Allergy Clin Immunol 2003 Aug;3(4):249-53. (cited by 1 analysis) October 2008
• Drug-induced liver injury. Handb Exp Pharmacol 2010(196):3-27. (cited by 1 analysis) December 2010
• Vitamin D toxicity, policy, and science. J. Bone Miner. Res. 2007 Dec;22:V64-8. (cited by 1 analysis) July 2008
• Metabolic consequences of drug misuse. Br J Anaesth 2000 Jul;85(1):136-42. (cited by 1 analysis) July 2008
• The vitamin A spectrum: from deficiency to toxicity. Am. J. Clin. Nutr. 2000 Apr;71(4):878-84. (cited by 1 analysis) December 2009
• Mercury toxicity and treatment: a review of the literature. J Environ Public Health 2012;2012:460508. (cited by 1 analysis) March 2012
• Bromide toxicity from consumption of dead sea salt. Am. J. Med. 2010 Mar;123(3):e11-2. (cited by 1 analysis) May 2012
• Pharmacogenetics of idiosyncratic adverse drug reactions. Handb Exp Pharmacol 2010(196):477-91. (cited by 1 analysis) December 2010
• Beyond toxicity: human health and the natural environment. Am J Prev Med 2001 Apr;20(3):234-40. (cited by 1 analysis) January 2012
• Inadequate toxicity tests of food additive acesulfame. Int J Occup Environ Health 2008;16(1):89-96. (cited by 1 analysis) January 2011
• Mitochondrial involvement in drug-induced liver injury. Handb Exp Pharmacol 2010(196):311-65. (cited by 1 analysis) December 2010
• The danger hypothesis applied to idiosyncratic drug reactions. Handb Exp Pharmacol 2010(196):493-509. (cited by 1 analysis) December 2010
• Membrane toxicity of antimicrobial compounds from essential oils. J. Agric. Food Chem. 2007 Jun 13;55(12):4863-70. (cited by 1 analysis) October 2008
• Adolescent drug addiction treatment and weight gain. J Addict Dis 2004;23(3):55-65. (cited by 1 analysis) June 2011
• Trace element risk assessment: essentiality vs. toxicity. Regul. Toxicol. Pharmacol. 2003 Oct;38(2):232-42. (cited by 1 analysis) February 2012
• Do drug company promotions influence physician behavior? West. J. Med. 2001 Apr;174(4):232-3. (cited by 1 analysis) July 2009
• Increased risk for vitamin A toxicity in severe hypertriglyceridemia. Ann. Intern. Med. 1986 Dec;105(6):877-9. (cited by 1 analysis) December 2009
• Common cellular and molecular mechanisms in obesity and drug addiction. Nat. Rev. Neurosci. 2011 Nov;12(11):638-51. (cited by 1 analysis) December 2011
• Intrinsic versus idiosyncratic drug-induced hepatotoxicity--two villains or one? J. Pharmacol. Exp. Ther. 2010 Mar;332(3):692-7. (cited by 1 analysis) December 2010
• Food and Drug Reward: Overlapping Circuits in Human Obesity and Addiction. Current topics in behavioral neuroscienc 2011 Oct 21. (cited by 1 analysis) December 2011
• Genetic and molecular factors in drug-induced liver injury: a review. Curr Drug Saf 2007 May;2(2):97-112. (cited by 1 analysis) December 2010
• Vitamin A: a drug for prevention of restenosis/reocclusion after percutaneous coronary intervention? Clin. Sci. 2008 Jan;114(1):19-25. (cited by 1 analysis) March 2008
• Astaxanthin protects beta-cells against glucose toxicity in diabetic db/db mice. Redox Rep. 2002;7(5):290-3. (cited by 1 analysis) March 2008
• Prevention and treatment considerations in patients with drug-induced gingival enlargement. Curr Opin Periodontol 1997;4:59-63. (cited by 1 analysis) May 2008
• Beyond alcohol and drug addiction. Does the negative trait of low distress tolerance have an association with overeating? Appetite 2011 Dec;57(3):578-81. (cited by 1 analysis) April 2012
• Effect of green tea and (-)-epigallocatechin gallate on ethanol-induced toxicity in HepG2 cells. Phytother Res 2008 May;22(5):669-74. (cited by 1 analysis) August 2010
• Zinc toxicity alters mitochondrial metabolism and leads to decreased ATP production in hepatocytes. J Appl Toxicol 2008 Mar;28(2):175-82. (cited by 1 analysis) October 2011
• The effect of orally administered melatonin on tissue accumulation and toxicity of cadmium in mice. J Trace Elem Med Biol 2006;19(4):259-65. (cited by 1 analysis) September 2011
• Determinants of glucose toxicity and its reversibility in the pancreatic islet beta-cell line, HIT-T15. Am. J. Physiol. Endocrinol. Metab. 2000 Nov;279(5):E997-1002. (cited by 1 analysis) November 2010
• New diet (NTP-2000) for rats in the National Toxicology Program toxicity and carcinogenicity studies. Fundam Appl Toxicol 1996 Jul;32(1):102-8. (cited by 1 analysis) December 2007
• Effects of vitamin D supplementation in atorvastatin-treated patients: a new drug interaction with an unexpected consequence. Clin. Pharmacol. Ther. 2009 Feb;85(2):198-203. (cited by 1 analysis) June 2009
• Neuroprotective effects of stearic acid against toxicity of oxygen/glucose deprivation or glutamate on rat cortical or hippocampal slices. Acta Pharmacol. Sin. 2006 Feb;27(2):145-50. (cited by 1 analysis) March 2008
• The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism. Diabetes 2002 Aug;51(8):2420-5. (cited by 1 analysis) March 2010
• Cod liver oil, vitamin A toxicity, frequent respiratory infections, and the vitamin D deficiency epidemic. Ann. Otol. Rhinol. Laryngol. 2008 Nov;117(11):864-70. (cited by 1 analysis) April 2010
• Treatment of statin adverse effects with supplemental Coenzyme Q10 and statin drug discontinuation. Biofactors 2005;25(1):147-52. (cited by 1 analysis) December 2007
• The potential value and toxicity of chromium picolinate as a nutritional supplement, weight loss agent and muscle development agent. Sports Med 2003;33(3):213-30. (cited by 1 analysis) April 2010
• Vitamin D toxicity redefined: vitamin K and the molecular mechanism. Med. Hypotheses 2007;68(5):1026-34. (cited by 1 analysis) August 2010
• Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver. Br. J. Nutr. 2007 Jan;97(1):58-66. (cited by 1 analysis) May 2011