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Paleo Diet for Fatty Liver

Paleo Diet for Fatty Liver

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Success stories and experiences on how the Paleo Diet has helped with Fatty Liver.

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From the Paleosphere

The Sweet Truth About Liver and Egg Yolks -- Choline Matters More to Fatty Liver Than Sugar, Alcohol, or Fat. The Daily Lipid (cites 12 articles) November 23, 2010
Does Your Liver Look Like an Eskimo's Dinner? Fatty Liver is a Silent Epidemic. The Daily Lipid (cites 3 articles) October 9, 2010
What Is Really Known about Fatty Liver?. Diabetes Update October 4, 2009
Choline and Fatty Liver. Whole Health Source (cites 2 articles) November 30, 2010
Another Fatty Liver Reversal. Whole Health Source June 29, 2009
Fatty Liver Reversal. Whole Health Source June 23, 2009
How to Reverse Fatty Liver. Diabetes Update March 13, 2009
Fatty Liver: It's not Just for Grown-ups Anymore. Whole Health Source (cites 2 articles) March 20, 2010
Another Fatty Liver Reversal, Part II. Whole Health Source September 25, 2009
Nonalcoholic Fatty Liver Disease. Whole Health Source (cites 2 articles) September 26, 2008
Does Green Tea Protect Against Fatty Liver Diseae?. The Daily Lipid (cites 1 article) January 14, 2012
Fatty Liver -- Behind Polycystic Ovarian Syndrome?. The Daily Lipid October 14, 2010
Eicosanoids, Fatty Liver and Insulin Resistance. Whole Health Source (cites 2 articles) May 23, 2009
Why Is My Cholesterol So High On This Diet? You May Be Curing Yourself of Fatty Liver. The Daily Lipid December 10, 2010
Does Choline Deficiency Contribute to Fatty Liver in Humans. The Daily Lipid (cites 8 articles) November 28, 2010
My New Wise Traditions Article on Nonalcoholic Fatty Liver Disease. The Daily Lipid April 7, 2011
New Fatty Liver Study Shows that Carbohydrate Restriction Causes Statistical Anomalies. The Daily Lipid (cites 1 article) April 22, 2011
Omega 3 Fatty Acids and their mechanisms. NephroPal June 9, 2010
Fatty Foods and Sugar Addictive Like Cocaine. Primal Wisdom November 3, 2011
Omega 3 Fatty Acid and Adiponectin Levels. NephroPal December 19, 2009
Omega-3 Fatty Acids, Antioxidants and Cancer. Cooling Inflammation March 5, 2009
ERA JUMP: Omega-3 fatty acids and plaque. The Heart Scan Blog July 31, 2008
Omega-3 fatty acids: Frequency vs. quantity. The Heart Scan Blog October 19, 2007
Liver; can you over do it?. Hyperlipid (cites 3 articles) December 2, 2009
More Liver. Whole Health Source April 29, 2008
Precious Yet Perilous -- Understanding the Essential Fatty Acids. The Daily Lipid October 8, 2010
Fatty Foods Release Memory-Improving Hormone. Primal Wisdom (cites 1 article) September 17, 2009
Liver and onions at 100 after Keep Fit. Hyperlipid January 17, 2010
How to Fatten Your Liver. Whole Health Source (cites 3 articles) September 23, 2008
Omega-3 Fatty Acids for Muscle Growth: Promising Potential. Leangains (cites 26 articles) May 15, 2011
Eden: Liver = Heart. Animal Pharm (cites 12 articles) July 8, 2008
Real Food VI: Liver. Whole Health Source May 2, 2008
The Liver: Your Metabolic Gatekeeper. Whole Health Source (cites 1 article) April 29, 2008
Food: Liver and bacon. Hyperlipid March 11, 2008
We Really Can Make Glucose From Fatty Acids After All! O Textbook, How Thy Biochemistry Hast Deceived Me!. The Daily Lipid January 7, 2012
Beef and Chicken Liver Pâté. Free the Animal December 21, 2011
Pork, Beef and Liver Terrine. Mark's Daily Apple August 6, 2011
Poor Sleep May Make You (and Your Liver) Fat. Mark's Daily Apple (cites 1 article) March 14, 2011
Liver and insulin (not a cooking recipe...). Hyperlipid (cites 3 articles) November 12, 2009
Estimated macronutrient and fatty acid intakes from an East African Paleolithic diet: Part 1. Primal Wisdom May 1, 2011
Silky-Smooth Chicken Liver Pâté. Mark's Daily Apple May 19, 2012
High Nutrition for Pennies: Liver and Onions. Free the Animal December 19, 2011
Dear Mark: Does the Liver Accumulate Toxins?. Mark's Daily Apple (cites 1 article) May 16, 2011
Anyone Doing Paleo Without Liver, Bones, Skin, and Greens?. The Daily Lipid March 16, 2011
Crispy Liver Hash Brown Patties. Mark's Daily Apple July 24, 2010
High Fructose Intake Raises Liver Fat. Diabetes Update (cites 3 articles) September 18, 2009
Nutrition Density Challenge: Fruit vs. Beef Liver. Free the Animal April 16, 2011
Yikes: Look What All That Starch Did to My Triglycerides and Alcohol to My Liver – New Lipid Panel and ALT Test. Free the Animal January 12, 2011
John Meadows Gets Jacked with Liver, Whole Eggs, and Red Palm Oil, and Wins "Mr. Ohio". The Daily Lipid October 9, 2010
Pepperoni Meatza, Liver & Onions, Tex-Thai Lamb Chili and Smoked Salmon Pasta. Free the Animal March 22, 2010
Podcast episode II: essential fatty acids, fish, and fish oil. The Healthy Skeptic May 27, 2010
Fructose Feeds Cancer Follow-up: Is all fructose metabolized in the liver?. Primal Wisdom (cites 1 article) August 21, 2010
Essential fatty acids are essential. Hyperlipid (cites 2 articles) January 9, 2008

Research References

Healthy intakes of n-3 and n-6 fatty acids: estimations considering worldwide diversity. Am. J. Clin. Nutr. 2006 Jun;83(6):1483S-1493S. (cited by 6 analyses) January 2012
Temporal changes in dietary fats: role of n-6 polyunsaturated fatty acids in excessive adipose tissue development and relationship to obesity. Prog. Lipid Res. 2006 May;45(3):203-36. (cited by 5 analyses) October 2010
Distinctive postprandial modulation of beta cell function and insulin sensitivity by dietary fats: monounsaturated compared with saturated fatty acids. Am. J. Clin. Nutr. 2008 Sep;88(3):638-44. (cited by 5 analyses) April 2010
Estimated macronutrient and fatty acid intakes from an East African Paleolithic diet. Br. J. Nutr. 2010 Dec;104(11):1666-87. (cited by 5 analyses) May 2011
Effects of winter stocker growth rate and finishing system on: III. Tissue proximate, fatty acid, vitamin, and cholesterol content. J. Anim. Sci. 2009 Sep;87(9):2961-70. (cited by 4 analyses) April 2011
The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp. Biol. Med. (Maywood) 2008 Jun;233(6):674-88. (cited by 4 analyses) June 2010
Fructose-induced fatty liver disease: hepatic effects of blood pressure and plasma triglyceride reduction. Hypertension 2005 May;45(5):1012-8. (cited by 3 analyses) September 2010
Biochemistry and physiology of n-3 fatty acids. FASEB J. 1992 May;6(8):2530-6. (cited by 3 analyses) May 2010
Non-alcoholic fatty liver disease: an overview of prevalence, diagnosis, pathogenesis and treatment considerations. Clin. Sci. 2008 Sep;115(5):141-50. (cited by 3 analyses) September 2010
Prolonged n-3 polyunsaturated fatty acid supplementation ameliorates hepatic steatosis in patients with non-alcoholic fatty liver disease: a pilot study. Aliment. Pharmacol. Ther. 2006 Apr 15;23(8):1143-51. (cited by 2 analyses) September 2008
Fructose consumption as a risk factor for non-alcoholic fatty liver disease. J. Hepatol. 2008 Jun;48(6):993-9. (cited by 2 analyses) May 2010
Nonalcoholic fatty liver disease in humans is associated with increased plasma endotoxin and plasminogen activator inhibitor 1 concentrations and with fructose intake. J. Nutr. 2008 Aug;138(8):1452-5. (cited by 2 analyses) March 2010
Liver and kidney metabolism during prolonged starvation. J. Clin. Invest. 1969 Mar;48(3):574-83. (cited by 3 analyses) April 2012
Effect of feeding systems on omega-3 fatty acids, conjugated linoleic acid and trans fatty acids in Australian beef cuts: potential impact on human health. Asia Pac J Clin Nutr 2006;15(1):21-9. (cited by 2 analyses) November 2011
High circulating leptin receptors with normal leptin sensitivity in liver-specific insulin receptor knock-out (LIRKO) mice. J. Biol. Chem. 2007 Aug 10;282(32):23672-8. (cited by 2 analyses) May 2011
Omega-3 fatty acids in inflammation and autoimmune diseases. J Am Coll Nutr 2002 Dec;21(6):495-505. (cited by 2 analyses) May 2010
Distribution, interconversion, and dose response of n-3 fatty acids in humans. Am. J. Clin. Nutr. 2006 Jun;83(6):1467S-1476S. (cited by 2 analyses) May 2010
Dietary flavonoids increase plasma very long-chain (n-3) fatty acids in rats. J. Nutr. 2011 Jan;141(1):37-41. (cited by 2 analyses) February 2012
Erythrocyte fatty acid profiles can predict acute non-fatal myocardial infarction. Br. J. Nutr. 2009 Nov;102(9):1355-61. (cited by 2 analyses) February 2010
Dietary n-6 and n-3 polyunsaturated fatty acids: from biochemistry to clinical implications in cardiovascular prevention. Biochem. Pharmacol. 2009 Mar 15;77(6):937-46. (cited by 3 analyses) February 2011
Dietary intake of fish vs. formulations leads to higher plasma concentrations of n-3 fatty acids. Lipids 2003 Apr;38(4):415-8. (cited by 2 analyses) June 2010
Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4 years of age. Pediatrics 2003 Jan;111(1):e39-44. (cited by 2 analyses) May 2010
Lack of suppression of circulating free fatty acids and hypercholesterolemia during weight loss on a high-fat, low-carbohydrate diet. Am. J. Clin. Nutr. 2010 Mar;91(3):578-85. (cited by 2 analyses) December 2010
Saturated and unsaturated fatty acids independently regulate low density lipoprotein receptor activity and production rate. J. Lipid Res. 1992 Jan;33(1):77-88. (cited by 2 analyses) September 2009
The effect of dietary omega-3 fatty acids on coronary atherosclerosis. A randomized, double-blind, placebo-controlled trial. Ann. Intern. Med. 1999 Apr 6;130(7):554-62. (cited by 2 analyses) June 2009
[Effect of n-3 fatty acids in glycemic and lipid profiles, oxidative stress and total antioxidant capacity in patients with the metabolic syndrome] Arq Bras Endocrinol Metabol 2010;54(5):463-9. (cited by 2 analyses) October 2010
Leptin receptor polymorphisms interact with polyunsaturated fatty acids to augment risk of insulin resistance and metabolic syndrome in adults. J. Nutr. 2010 Feb;140(2):238-44. (cited by 2 analyses) October 2010
Effects of reducing dietary saturated fatty acids on plasma lipids and lipoproteins in healthy subjects: the DELTA Study, protocol 1. Arterioscler. Thromb. Vasc. Biol. 1998 Mar;18(3):441-9. (cited by 2 analyses) February 2010
No evidence of differential effects of SFA, MUFA or PUFA on post-ingestive satiety and energy intake: a randomised trial of fatty acid saturation. Nutr J 2010;9:24. (cited by 2 analyses) November 2010
Diet and disease--the Israeli paradox: possible dangers of a high omega-6 polyunsaturated fatty acid diet. Isr. J. Med. Sci. 1996 Nov;32(11):1134-43. (cited by 2 analyses) February 2012
The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomed. Pharmacother. 2002 Oct;56(8):365-79. (cited by 2 analyses) February 2012
An omega-3 polyunsaturated fatty acid concentrate increases plasma high-density lipoprotein 2 cholesterol and paraoxonase levels in patients with familial combined hyperlipidemia. Metab. Clin. Exp. 2004 Feb;53(2):153-8. (cited by 2 analyses) July 2009
Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance. Circulation 2002 Oct 8;106(15):1925-9. (cited by 2 analyses) May 2011
Serum Phospholipid Fatty Acids and Prostate Cancer Risk: Results From the Prostate Cancer Prevention Trial. American journal of epidemiology 2011 Apr 24. (cited by 2 analyses) April 2011
Fatty liver: a novel component of the metabolic syndrome. Arterioscler. Thromb. Vasc. Biol. 2008 Jan;28(1):27-38. (cited by 2 analyses) January 2011
Polymorphism of the PEMT gene and susceptibility to nonalcoholic fatty liver disease (NAFLD). FASEB J. 2005 Aug;19(10):1266-71. (cited by 2 analyses) December 2010
Dietary saturated fatty acids reverse inflammatory and fibrotic changes in rat liver despite continued ethanol administration. J. Pharmacol. Exp. Ther. 2001 Nov;299(2):638-44. (cited by 2 analyses) December 2009
The liver in obesity. AMA Arch Intern Med 1952 Aug;90(2):141-56. (cited by 2 analyses) November 2010
Difference in the metabolism of vitamin K between liver and bone in vitamin K-deficient rats. Br. J. Nutr. 2002 Apr;87(4):307-14. (cited by 2 analyses) March 2009
High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology 2010 Sep;52(3):934-44. (cited by 2 analyses) September 2010
Cafeteria diet is a robust model of human metabolic syndrome with liver and adipose inflammation: comparison to high-fat diet. Obesity (Silver Spring) 2011 Jun;19(6):1109-17. (cited by 2 analyses) September 2011
Biological control of phytopathogenic fungi by fatty acids. Mycopathologia 2008 Aug;166(2):93-102. (cited by 2 analyses) September 2009
Membrane fatty acids as pacemakers of animal metabolism. Lipids 2007 Sep;42(9):811-9. (cited by 2 analyses) September 2010
Polyunsaturated fatty acids in the food chain in the United States. Am. J. Clin. Nutr. 2000 Jan;71(1):179S-88S. (cited by 2 analyses) January 2011
Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol. Cell 1999 Mar;3(3):397-403. (cited by 2 analyses) October 2009
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nature immunology 2011 Apr 10. (cited by 2 analyses) April 2011
Feeding regimes affect fatty acid composition in Australian beef cattle. Asia Pac J Clin Nutr 2003;12:S38. (cited by 2 analyses) August 2008
Carcinogen-induced lesions in the rat pancreas: effects of varying levels of essential fatty acid. Cancer Res. 1985 Nov;45(11):5252-6. (cited by 2 analyses) January 2009
Dietary lipid profile is a determinant of tissue phospholipid fatty acid composition and rate of weight gain in rats. J. Nutr. 1993 Mar;123(3):512-9. (cited by 2 analyses) January 2010
Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion. Proc. Natl. Acad. Sci. U.S.A. 2003 Feb 18;100(4):1751-6. (cited by 2 analyses) September 2010
Western diet, but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats. Biochem. J. 2007 Sep 15;406(3):457-67. (cited by 2 analyses) September 2009
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J. Biol. Chem. 2002 Dec 27;277(52):50230-6. (cited by 2 analyses) September 2010
EFFECT OF VERY SMALL CONCENTRATIONS OF INSULIN ON FOREARM METABOLISM. PERSISTENCE OF ITS ACTION ON POTASSIUM AND FREE FATTY ACIDS WITHOUT ITS EFFECT ON GLUCOSE. J. Clin. Invest. 1964 May;43:950-62. (cited by 2 analyses) August 2011
Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid. Diabetes 1991 Feb;40(2):280-9. (cited by 2 analyses) April 2011
Long-term effect of varying the source or amount of dietary carbohydrate on postprandial plasma glucose, insulin, triacylglycerol, and free fatty acid concentrations in subjects with impaired glucose tolerance. Am. J. Clin. Nutr. 2003 Mar;77(3):612-21. (cited by 2 analyses) March 2009
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J. Clin. Invest. 2005 May;115(5):1343-51. (cited by 1 analysis) November 2010
Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease. Diabetes Metab. 2003 Nov;29(5):478-85. (cited by 1 analysis) November 2010
Nonalcoholic fatty liver disease. N. Engl. J. Med. 2002 Apr 18;346(16):1221-31. (cited by 1 analysis) October 2010
Therapeutic potential of green tea in nonalcoholic fatty liver disease. Nutr. Rev. 2012 Jan;70(1):41-56. (cited by 1 analysis) January 2012
Dietary and physical activity patterns in children with fatty liver. European journal of clinical nutrition 2010 Mar 10. (cited by 1 analysis) March 2010
Dietary and physical activity patterns in children with fatty liver European Journal of Clinical Nutrition 2010 Mar. (cited by 1 analysis) May 2010
Choline-deficiency fatty liver: impaired release of hepatic triglycerides. J. Lipid Res. 1968 Jul;9(4):437-46. (cited by 1 analysis) November 2010
COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver. Obesity (Silver Spring) 2009 Jun;17(6):1150-7. (cited by 1 analysis) May 2009
Efficiency of intermittent exercise on adiposity and fatty liver in rats fed with high-fat diet. Obesity (Silver Spring) 2008 Oct;16(10):2217-22. (cited by 1 analysis) June 2009
Influence of polygenetic polymorphisms on the susceptibility to non-alcoholic fatty liver disease of Chinese people. J. Gastroenterol. Hepatol. 2010 Apr;25(4):772-7. (cited by 1 analysis) December 2010
Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men. Proc. Natl. Acad. Sci. U.S.A. 2006 Nov 28;103(48):18273-7. (cited by 1 analysis) September 2010
Omega-3 fatty acids improve liver and pancreas function in postoperative cancer patients. Int. J. Cancer 2004 Sep 10;111(4):611-6. (cited by 1 analysis) January 2009
Effects of trans-10,cis-12 CLA on liver size and fatty acid oxidation under energy restriction conditions in hamsters. Nutrition 2011 Jan;27(1):116-21. (cited by 1 analysis) May 2011
The effect of essential fatty acid deficiency on basal respiration and function of liver mitochondria in rats. J. Nutr. 1984 Feb;114(2):255-62. (cited by 1 analysis) December 2008
Cardiac abnormalities as a new manifestation of nonalcoholic fatty liver disease: echocardiographic and tissue Doppler imaging assessment. J. Clin. Gastroenterol. 2000 Aug;40(10):949-55. (cited by 1 analysis) May 2008
Metabolic activity of the enteric microbiota influences the fatty acid composition of murine and porcine liver and adipose tissues. Am. J. Clin. Nutr. 2009 May;89(5):1393-401. (cited by 1 analysis) May 2010
Fish oil improves lipid metabolism and ameliorates inflammation in patients with metabolic syndrome: Impact of nonalcoholic fatty liver disease. Pharm Biol 2011 Nov 21. (cited by 1 analysis) January 2012
Effect of ethanol and thermally oxidized sunflower oil ingestion on phospholipid fatty acid composition of rat liver: protective role of Cuminum cyminum L. Ann. Nutr. Metab. 2008 Nov;49(5):300-3. (cited by 1 analysis) August 2011
Voluntary oral feeding of rats not requiring a very high fat diet is a clinically relevant animal model of non-alcoholic fatty liver disease (NAFLD). Histol. Histopathol. 2009 Sep;24(9):1161-9. (cited by 1 analysis) September 2009
Statin induction of liver fatty acid-binding protein (L-FABP) gene expression is peroxisome proliferator-activated receptor-alpha-dependent. J. Biol. Chem. 2004 Oct 29;279(44):45512-8. (cited by 1 analysis) July 2008
Dietary saturated fatty acids down-regulate cyclooxygenase-2 and tumor necrosis factor alfa and reverse fibrosis in alcohol-induced liver disease in the rat. Hepatology 1997 Dec;26(6):1538-45. (cited by 1 analysis) December 2009
Atorvastatin treatment induced peroxisome proliferator-activated receptor alpha expression and decreased plasma nonesterified fatty acids and liver triglyceride in fructose-fed rats. J. Pharmacol. Exp. Ther. 2002 Jul;302(1):232-9. (cited by 1 analysis) July 2008
The lowering of hepatic fatty acid uptake improves liver function and insulin sensitivity without affecting hepatic fat content in humans. Am. J. Physiol. Endocrinol. Metab. 2008 Aug;295(2):E413-9. (cited by 1 analysis) September 2009
Dietary trans 10, cis 12-conjugated linoleic acid reduces the expression of fatty acid oxidation and drug detoxification enzymes in mouse liver. Br. J. Nutr. 2007 Jan;97(1):58-66. (cited by 1 analysis) May 2011
Drug-induced liver injury. Handb Exp Pharmacol 2010(196):3-27. (cited by 1 analysis) December 2010
Insulin action on the liver in vivo. Biochem. Soc. Trans. 2007 Nov;35:1171-4. (cited by 1 analysis) February 2011
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IgA antibodies to dietary antigens in liver cirrhosis. Ric Clin Lab 1995 Dec;17(3):235-42. (cited by 1 analysis) April 2009
The involvement of endotoxin in halothane-associated liver injury. Anesthesiology 1984 Nov;61(5):544-50. (cited by 1 analysis) December 2010
Omega-3 fatty acids as treatments for mental illness: which disorder and which fatty acid? Lipids Health Dis 2007;6:21. (cited by 1 analysis) January 2009
Fatty acid facts, Part I. Essential fatty acids as treatment for depression, or food for mood? Drug News Perspect. 2008 Oct;21(8):446-51. (cited by 1 analysis) May 2011
Mitochondrial involvement in drug-induced liver injury. Handb Exp Pharmacol 2010(196):311-65. (cited by 1 analysis) December 2010
Visceral fat: a key mediator of steatohepatitis in metabolic liver disease. Hepatology 2008 Aug;48(2):449-57. (cited by 1 analysis) December 2008
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Peroxisome proliferation in liver of rats fed oxidized frying oil. J. Nutr. Sci. Vitaminol. 2005 Oct;51(5):361-8. (cited by 1 analysis) March 2011
The influence of diet on the lipogenic response to thyroxine in rat liver. Life Sci. 1975 Dec 15;17(12):1785-97. (cited by 1 analysis) December 2008
Coordinate regulation of gallbladder motor function in the gut-liver axis. Hepatology 2008 Jun;47(6):2112-26. (cited by 1 analysis) July 2010
Inhibition of triiodothyronine's induction of rat liver lipogenic enzymes by dietary fat. J. Nutr. 1990 Jun;120(6):625-30. (cited by 1 analysis) December 2008
Role of the human liver in the assimilation of intravenously administered fructose. Metab. Clin. Exp. 1953 Sep;2(5):450-8. (cited by 1 analysis) October 2010
Genetic and molecular factors in drug-induced liver injury: a review. Curr Drug Saf 2007 May;2(2):97-112. (cited by 1 analysis) December 2010
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