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Paleo Diet for Glucose Intolerance

Paleo Diet for Glucose Intolerance

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Success stories and experiences on how the Paleo Diet has helped with Glucose Intolerance.

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From the Paleosphere

LACTOSE INTOLERANCE. NephroPal September 15, 2010
Wheat intolerance. Conditioning Research June 14, 2010
Genetics of Food Intolerance. Cooling Inflammation April 19, 2012
Extreme carbohydrate intolerance. The Heart Scan Blog August 24, 2010
CIS: Carbohydrate intolerance syndrome. The Heart Scan Blog January 27, 2009
Dr. Oz, Constipation, Soluble Fiber, Food Intolerance. Cooling Inflammation March 1, 2012
Antibiotics, Gut Flora, Food Intolerance and Disease. Cooling Inflammation April 22, 2010
Blood glucose 160. The Heart Scan Blog February 25, 2011
Blood glucose 160. The Heart Scan Blog February 25, 2011
Helicobacter and glucose. Hyperlipid (cites 4 articles) March 30, 2008
Construct your glucose curve. The Heart Scan Blog February 19, 2011
Construct your glucose curve. The Heart Scan Blog February 19, 2011
Glucose, lactate and cancer. Hyperlipid (cites 4 articles) November 22, 2009
On zero carbs, can you make your glucose from fat?. PaNu Blog August 25, 2009
Fructose vs. Glucose Showdown. Whole Health Source April 22, 2009
Fructose, Glucose and Cholesterol. Hyperlipid (cites 2 articles) March 6, 2009
Familial Hypercholesterolaemia and glucose. Hyperlipid (cites 1 article) August 26, 2008
Glucose as a cure for hypertriglyceridaemia?. Hyperlipid (cites 2 articles) March 13, 2008
Glucose Tolerance in Non-industrial Cultures. Whole Health Source (cites 3 articles) November 21, 2010
New Widget Converts A1c/Glucose/mg/dl/mmol/L. Diabetes Update May 25, 2008
Better Blood Glucose with Lower Meal Frequency. Leangains (cites 4 articles) January 4, 2011
Normal fasting glucose with high HbA1c. The Heart Scan Blog March 23, 2010
It's never too late to normalise your glucose (so long as you are still alive). Hyperlipid (cites 1 article) March 16, 2009
We Really Can Make Glucose From Fatty Acids After All! O Textbook, How Thy Biochemistry Hast Deceived Me!. The Daily Lipid January 7, 2012
A Massive Long Term Study Sheds More Light on Truly Normal Fasting Glucose Values. Diabetes Update July 3, 2008
The Formulas equating HbA1c to Average Glucose Level Don't Work with Near Normal Blood sugars?. Diabetes Update December 20, 2006
Study Finds Dreamfields Pasta Produces Identical Glucose Curves as Regular Dry Pasta. Diabetes Update (cites 1 article) February 8, 2011
Glucose restriction extends lifespan of human cells, kills human cancer cells. Primal Wisdom (cites 3 articles) December 19, 2009

Research References

A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease. Diabetologia 2007 Sep;50(9):1795-807. (cited by 8 analyses) May 2011
Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans. J. Clin. Invest. 2009 May;119(5):1322-34. (cited by 5 analyses) January 2011
Training in the fasted state improves glucose tolerance during fat-rich diet. J. Physiol. (Lond.) 2010 Nov 1;588:4289-302. (cited by 4 analyses) April 2012
Inflammation markers and metabolic characteristics of subjects with 1-h plasma glucose levels. Diabetes Care 2010 Feb;33(2):411-3. (cited by 3 analyses) May 2011
Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes. J. Clin. Endocrinol. Metab. 2000 Aug;85(8):2970-3. (cited by 3 analyses) May 2010
Effects of intensive glucose lowering in type 2 diabetes. N. Engl. J. Med. 2008 Jun 12;358(24):2545-59. (cited by 2 analyses) May 2009
Relation between blood glucose and coronary mortality over 33 years in the Whitehall Study. Diabetes Care 2006 Jan;29(1):26-31. (cited by 2 analyses) November 2010
Rosuvastatin treatment is associated with an increase in insulin resistance in hyperlipidaemic patients with impaired fasting glucose. Int. J. Clin. Pract. 2009 Sep;63(9):1308-13. (cited by 2 analyses) November 2009
Nonenzymatic glycation of bovine serum albumin by fructose (fructation). Comparison with the Maillard reaction initiated by glucose. J. Biol. Chem. 1989 Mar 5;264(7):3674-9. (cited by 2 analyses) October 2010
Blood pressure is reduced and insulin sensitivity increased in glucose-intolerant, hypertensive subjects after 15 days of consuming high-polyphenol dark chocolate. J. Nutr. 2008 Sep;138(9):1671-6. (cited by 2 analyses) February 2012
Long-term effect of varying the source or amount of dietary carbohydrate on postprandial plasma glucose, insulin, triacylglycerol, and free fatty acid concentrations in subjects with impaired glucose tolerance. Am. J. Clin. Nutr. 2003 Mar;77(3):612-21. (cited by 2 analyses) March 2009
Metabolic responses to oral glucose in the Kalahari Bushmen. Br Med J 1971 Oct 23;4(5781):206-8. (cited by 2 analyses) November 2010
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N. Engl. J. Med. 2008 Jun 12;358(24):2560-72. (cited by 2 analyses) May 2009
Increased prevalence of impaired glucose tolerance in patients with painful sensory neuropathy. Diabetes Care 2001 Aug;24(8):1448-53. (cited by 2 analyses) November 2010
Self-selected macronutrient diet affects energy and glucose metabolism in brown fat-ablated mice. Obes. Res. 2003 Dec;11(12):1536-44. (cited by 2 analyses) September 2008
Mechanism of action of insulin in diabetic patients: a dose-related effect on glucose production and utilisation. Br Med J 1978 May 13;1(6122):1239-42. (cited by 2 analyses) October 2011
Longitudinal adaptations to very low-carbohydrate weight-reduction diet in obese rats: body composition and glucose tolerance. Obesity (Silver Spring) 2010 Aug;18(8):1538-44. (cited by 2 analyses) September 2010
Improvement of glucose tolerance and hepatic insulin sensitivity by oligofructose requires a functional glucagon-like peptide 1 receptor. Diabetes 2006 May;55(5):1484-90. (cited by 2 analyses) February 2010
A double-blind, placebo-controlled test of 2 d of calorie deprivation: effects on cognition, activity, sleep, and interstitial glucose concentrations. Am. J. Clin. Nutr. 2008 Sep;88(3):667-76. (cited by 2 analyses) October 2010
Intensive glucose-lowering therapy reduces cardiovascular disease events in veterans affairs diabetes trial participants with lower calcified coronary atherosclerosis. Diabetes 2009 Nov;58(11):2642-8. (cited by 2 analyses) December 2010
Stimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive mice. Diabetes 2011 Dec;60(12):3132-40. (cited by 2 analyses) December 2011
EFFECT OF VERY SMALL CONCENTRATIONS OF INSULIN ON FOREARM METABOLISM. PERSISTENCE OF ITS ACTION ON POTASSIUM AND FREE FATTY ACIDS WITHOUT ITS EFFECT ON GLUCOSE. J. Clin. Invest. 1964 May;43:950-62. (cited by 2 analyses) August 2011
Dietary change and obesity associated with glucose intolerance in Alaska Natives. J Am Diet Assoc 1995 Jun;95(6):676-82. (cited by 1 analysis) July 2008
Cassia cinnamon for the attenuation of glucose intolerance and insulin resistance resulting from sleep loss. J Med Food 2009 Jun;12(3):467-72. (cited by 1 analysis) May 2010
A high oxidised frying oil content diet is less adipogenic, but induces glucose intolerance in rodents. Br. J. Nutr. 2007 Jul;98(1):63-71. (cited by 1 analysis) February 2011
Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: an adipokine-mediated process? Diabetes 2002 Oct;51(10):2951-8. (cited by 1 analysis) March 2008
Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance. Dev. Cell 2002 Jul;3(1):25-38. (cited by 1 analysis) January 2012
Body iron stores and glucose intolerance in premenopausal women: role of hyperandrogenism, insulin resistance, and genomic variants related to inflammation, oxidative stress, and iron metabolism. Diabetes Care 2009 Aug;32(8):1525-30. (cited by 1 analysis) July 2011
Mitochondrial myopathies: diagnosis, exercise intolerance, and treatment options. Med Sci Sports Exerc 2005 Dec;37(12):2086-93. (cited by 1 analysis) March 2009
Proteolysis by sourdough lactic acid bacteria: effects on wheat flour protein fractions and gliadin peptides involved in human cereal intolerance. Appl. Environ. Microbiol. 2002 Feb;68(2):623-33. (cited by 1 analysis) June 2010
[Fatal consequences of fructose infusion in undiagnosed fructose intolerance]. Dtsch. Med. Wochenschr. 1988 Jun 10;113(23):945-7. (cited by 1 analysis) May 2012
The role of adipose cell size and adipose tissue insulin sensitivity in the carbohydrate intolerance of human obesity. J. Clin. Invest. 1968 Jan;47(1):153-65. (cited by 1 analysis) October 2011
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity. Nature 2007 Sep 13;449(7159):228-32. (cited by 1 analysis) February 2011
Variation of interstitial glucose measurements assessed by continuous glucose monitors in healthy, nondiabetic individuals. Diabetes Care 2010 Jun;33(6):1297-9. (cited by 1 analysis) November 2010
Short-term peaks in glucose promote renal fibrogenesis independently of total glucose exposure. Am. J. Physiol. Renal Physiol. 2004 Aug;287(2):F268-73. (cited by 1 analysis) April 2009
Acute intravenous leptin infusion increases glucose turnover but not skeletal muscle glucose uptake in ob/ob mice. Diabetes 1999 Jun;48(6):1264-9. (cited by 1 analysis) November 2010
Beta-cell dysfunction in subjects with impaired glucose tolerance and early type 2 diabetes: comparison of surrogate markers with first-phase insulin secretion from an intravenous glucose tolerance test. Diabetes 2008 Jun;57(6):1638-44. (cited by 1 analysis) June 2008
Variability among five over-the-counter blood glucose monitors. Clin. Chim. Acta 2006 Feb;364(1):292-7. (cited by 1 analysis) July 2009
The business of self-monitoring of blood glucose: a market profile. J Diabetes Sci Technol 2009;3(5):1219-23. (cited by 1 analysis) January 2011
PPARdelta regulates glucose metabolism and insulin sensitivity. Proc. Natl. Acad. Sci. U.S.A. 2006 Feb 28;103(9):3444-9. (cited by 1 analysis) May 2008
Low vitamin K intake effects on glucose tolerance in rats. Int J Vitam Nutr Res 1999 Jan;69(1):27-31. (cited by 1 analysis) June 2008
Glucose tolerance in adults after prenatal exposure to famine. Lancet 1998 Jan 17;351(9097):173-7. (cited by 1 analysis) October 2010
Leptin and the central nervous system control of glucose metabolism. Physiol. Rev. 2011 Apr;91(2):389-411. (cited by 1 analysis) October 2011
Glucose normalization and outcomes in patients with acute myocardial infarction. Arch. Intern. Med. 2009 Mar 9;169(5):438-46. (cited by 1 analysis) March 2009
Glucose control and vascular complications in veterans with type 2 diabetes. N. Engl. J. Med. 2009 Jan 8;360(2):129-39. (cited by 1 analysis) February 2009
10-year follow-up of intensive glucose control in type 2 diabetes. N. Engl. J. Med. 2008 Oct 9;359(15):1577-89. (cited by 1 analysis) September 2008
The relationship between carbohydrate intake and glucose tolerance in pregnant women. Acta Obstet Gynecol Scand 2003 Dec;82(12):1080-5. (cited by 1 analysis) October 2007
Intermittent fasting does not affect whole-body glucose, lipid, or protein metabolism. Am. J. Clin. Nutr. 2009 Nov;90(5):1244-51. (cited by 1 analysis) April 2011
Systematic review: glucose control and cardiovascular disease in type 2 diabetes. Ann. Intern. Med. 2009 Sep 15;151(6):394-403. (cited by 1 analysis) September 2009
Methylglyoxal and glucose metabolism: a historical perspective and future avenues for research. Drug Metabol Drug Interact 2008;23(1):69-91. (cited by 1 analysis) July 2009
Normal fasting plasma glucose levels and type 2 diabetes in young men. N. Engl. J. Med. 2005 Oct 6;353(14):1454-62. (cited by 1 analysis) November 2010
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis Nature Medicine 2005 Feb;11(3):320. (cited by 1 analysis) May 2008
Astaxanthin protects beta-cells against glucose toxicity in diabetic db/db mice. Redox Rep. 2002;7(5):290-3. (cited by 1 analysis) March 2008
In vivo evidence for increased oxidation of circulating LDL in impaired glucose tolerance. Diabetes 2002 Oct;51(10):3102-6. (cited by 1 analysis) August 2009
Daily magnesium supplements improve glucose handling in elderly subjects. Am. J. Clin. Nutr. 1992 Jun;55(6):1161-7. (cited by 1 analysis) February 2010
Importance of blood glucose concentration in regulating lipolysis during fasting in humans. Am. J. Physiol. 1990 Jan;258(1):E32-9. (cited by 1 analysis) October 2010
Regulation of glucose and ketone-body metabolism in brain of anaesthetized rats. Biochem. J. 1974 Jan;138(1):1-10. (cited by 1 analysis) November 2009
Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport Nature Medicine 2011 Aug. (cited by 1 analysis) August 2011
Trans-10,cis-12-CLA dysregulate lipid and glucose metabolism and induce hepatic NR4A receptors. Front Biosci (Elite Ed) 2010;2:87-97. (cited by 1 analysis) May 2011
C. elegans as model for the study of high glucose- mediated life span reduction. Diabetes 2009 Nov;58(11):2450-6. (cited by 1 analysis) May 2010
Repeated measures of serum glucose and insulin in relation to postmenopausal breast cancer. Int. J. Cancer 2009 Dec 1;125(11):2704-10. (cited by 1 analysis) January 2011
Glucose tolerance and skeletal muscle gene expression in response to alternate day fasting. Obes. Res. 2005 Mar;13(3):574-81. (cited by 1 analysis) June 2008
Postprandial glucose, insulin, and incretin responses to grain products in healthy subjects. Am. J. Clin. Nutr. 2002 Feb;75(2):254-62. (cited by 1 analysis) March 2010
De novo lipogenesis during controlled overfeeding with sucrose or glucose in lean and obese women. Am. J. Clin. Nutr. 2001 Dec;74(6):737-46. (cited by 1 analysis) November 2010
Dietary restriction and glucose regulation in aging rhesus monkeys: a follow-up report at 8.5 yr. Am. J. Physiol. Endocrinol. Metab. 2001 Oct;281(4):E757-65. (cited by 1 analysis) July 2009
Determinants of glucose toxicity and its reversibility in the pancreatic islet beta-cell line, HIT-T15. Am. J. Physiol. Endocrinol. Metab. 2000 Nov;279(5):E997-1002. (cited by 1 analysis) November 2010
Increased blood glucose and insulin, body size, and incident colorectal cancer. J. Natl. Cancer Inst. 1999 Jul 7;91(13):1147-54. (cited by 1 analysis) January 2008
Metabolism of pyruvate and glucose by intact cells of Helicobacter pylori studied by 13C NMR spectroscopy. Microbiology (Reading, Engl.) 1994 Aug;140:2085-92. (cited by 1 analysis) March 2008
Leucine, glucose, and energy metabolism after 3 days of fasting in healthy human subjects. Am. J. Clin. Nutr. 1987 Oct;46(4):557-62. (cited by 1 analysis) October 2010
The acute effects of four protein meals on insulin, glucose, appetite and energy intake in lean men. Br. J. Nutr. 2010 Oct;104(8):1241-8. (cited by 1 analysis) August 2011
Mitochondrial dysfunction is induced by high levels of glucose and free fatty acids in 3T3-L1 adipocytes. Mol. Cell. Endocrinol. 2010 May 14;320(1):25-33. (cited by 1 analysis) October 2011
Changes in glucose tolerance and insulin sensitivity following 2 weeks of daily cinnamon ingestion in healthy humans. Eur. J. Appl. Physiol. 2009 Apr;105(6):969-76. (cited by 1 analysis) May 2010
Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J. Exp. Med. 2008 Sep 29;205(10):2409-17. (cited by 1 analysis) April 2011
Control of blood glucose in type 2 diabetes without weight loss by modification of diet composition. Nutrition & metabolism 2006;3:16. (cited by 1 analysis) April 2008
Early improvement of glucose tolerance after ileal transposition in a non-obese type 2 diabetes rat model. Obes Surg 2005 Oct;15(9):1258-64. (cited by 1 analysis) May 2008
Caffeine ingestion decreases glucose disposal during a hyperinsulinemic-euglycemic clamp in sedentary humans. Diabetes 2001 Oct;50(10):2349-54. (cited by 1 analysis) February 2010
Regulatory function of glucose and insulin on high-density lipoprotein cholesterol in normolipidemic subjects. Metab. Clin. Exp. 1994 Nov;43(11):1332-7. (cited by 1 analysis) June 2008
Cardiovascular disease mortality in Europeans in relation to fasting and 2-h plasma glucose levels within a normoglycemic range. Diabetes Care 2010 Oct;33(10):2211-6. (cited by 1 analysis) October 2010
Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels. Appetite 2010 Aug;55(1):37-43. (cited by 1 analysis) February 2011
Peak-time determination of post-meal glucose excursions in insulin-treated diabetic patients. Diabetes Metab. 2010 Apr;36(2):165-9. (cited by 1 analysis) March 2012
Minimal contribution of fasting hyperglycemia to the incidence of type 2 diabetes in subjects with normal 2-h plasma glucose. Diabetes Care 2010 Mar;33(3):557-61. (cited by 1 analysis) March 2010
Vinegar ingestion at bedtime moderates waking glucose concentrations in adults with well-controlled type 2 diabetes. Diabetes Care 2007 Nov;30(11):2814-5. (cited by 1 analysis) April 2011
High glucose increases the expression of Cbfa1 and BMP-2 and enhances the calcification of vascular smooth muscle cells. Nephrol. Dial. Transplant. 2006 Dec;21(12):3435-42. (cited by 1 analysis) March 2008
Effect of a high-protein, low-carbohydrate diet on blood glucose control in people with type 2 diabetes. Diabetes 2004 Sep;53(9):2375-82. (cited by 1 analysis) September 2009
Effects of free fatty acids (FFA) on glucose metabolism: significance for insulin resistance and type 2 diabetes. Exp. Clin. Endocrinol. Diabetes 2003 May;111(3):121-4. (cited by 1 analysis) August 2011
Magnesium reduces insulin-stimulated glucose uptake and serum lipid concentrations in type 1 diabetes. Metab. Clin. Exp. 2001 Dec;50(12):1409-17. (cited by 1 analysis) October 2009
Prevalence of diabetes and impaired fasting glucose in Korea: Korean National Health and Nutrition Survey 2001. Diabetes Care 2006 Feb;29(2):226-31. (cited by 1 analysis) February 2012
Neuroprotective effects of stearic acid against toxicity of oxygen/glucose deprivation or glutamate on rat cortical or hippocampal slices. Acta Pharmacol. Sin. 2006 Feb;27(2):145-50. (cited by 1 analysis) March 2008
Direct metabolic regulation in skeletal muscle and fat tissue by leptin: implications for glucose and fatty acids homeostasis. Int J Obes (Lond) 2005 Oct;29(10):1175-83. (cited by 1 analysis) November 2010
Vinegar supplementation lowers glucose and insulin responses and increases satiety after a bread meal in healthy subjects. Eur J Clin Nutr 2005 Sep;59(9):983-8. (cited by 1 analysis) April 2011
The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years. Diabetes Care 1999 Feb;22(2):233-40. (cited by 1 analysis) November 2010
Long-term evolution of the effect of bran ingestion on meal-induced glucose and insulin responses in healthy man. Am. J. Clin. Nutr. 1984 Nov;40(5):1023-6. (cited by 1 analysis) October 2008
Fasting versus postload plasma glucose concentration and the risk for future type 2 diabetes: results from the Botnia Study. Diabetes Care 2009 Feb;32(2):281-6. (cited by 1 analysis) January 2011
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab. 2007 Oct;6(4):280-93. (cited by 1 analysis) July 2010
Independent associations of fasting insulin, glucose, and glycated haemoglobin with stroke and coronary heart disease in older women. PLoS Med. 2007 Aug;4(8):e263. (cited by 1 analysis) June 2008
Impact of fasting plasma glucose levels on gastric cancer incidence in a general Japanese population: the Hisayama study. Diabetes Care 2005 Apr;28(4):789-94. (cited by 1 analysis) March 2008
Effect of a low-carbohydrate diet on appetite, blood glucose levels, and insulin resistance in obese patients with type 2 diabetes. Ann. Intern. Med. 2005 Mar 15;142(6):403-11. (cited by 1 analysis) August 2011
Rebaudioside A potently stimulates insulin secretion from isolated mouse islets: studies on the dose-, glucose-, and calcium-dependency. Metab. Clin. Exp. 2004 Oct;53(10):1378-81. (cited by 1 analysis) February 2011
Aspartame ingestion with and without carbohydrate in phenylketonuric and normal subjects: effect on plasma concentrations of amino acids, glucose, and insulin. Metab. Clin. Exp. 1990 Apr;39(4):391-6. (cited by 1 analysis) February 2011
Postprandial glucose, insulin, free fatty acid and growth hormone responses in children consuming all the day's protein in one meal. Am. J. Clin. Nutr. 1976 Sep;29(9):984-8. (cited by 1 analysis) August 2011

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